KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
10
Human Site:
S170
Identified Species:
13.75
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S170
T
L
A
A
G
T
S
S
P
K
T
E
G
K
H
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S170
T
L
A
A
G
T
S
S
P
K
T
E
G
K
H
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
P170
L
A
A
G
T
S
S
P
K
T
E
G
K
H
E
Dog
Lupus familis
XP_533766
1089
122761
S170
T
L
A
V
D
S
L
S
P
K
T
E
G
K
C
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
P170
V
G
T
P
S
P
V
P
E
D
K
H
E
E
T
Rat
Rattus norvegicus
NP_446123
1093
121882
V170
A
V
G
T
P
S
P
V
P
E
G
K
R
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
L170
S
A
V
P
L
K
K
L
E
E
A
I
P
R
L
Chicken
Gallus gallus
O42184
1433
161009
T174
P
S
G
I
P
Q
K
T
S
P
L
A
A
K
E
Frog
Xenopus laevis
Q5PQ23
649
75475
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
V170
S
E
Q
N
S
S
T
V
E
E
Q
M
Q
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
K122
G
D
V
P
S
V
A
K
R
L
S
E
S
S
L
Honey Bee
Apis mellifera
XP_394037
1326
150590
N197
V
N
D
C
S
N
S
N
I
N
N
P
K
I
V
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
A752
D
K
K
K
C
A
E
A
I
M
S
K
L
V
N
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
S170
L
L
Q
D
S
D
D
S
D
E
I
D
K
E
R
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
V165
V
P
E
S
V
D
D
V
Q
G
K
E
I
S
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
D146
T
V
V
L
D
P
K
D
D
E
P
Q
S
Q
I
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
13.3
66.6
N.A.
0
6.6
N.A.
0
6.6
0
0
N.A.
6.6
6.6
0
13.3
P-Site Similarity:
100
100
20
73.3
N.A.
6.6
40
N.A.
20
13.3
0
26.6
N.A.
20
13.3
26.6
33.3
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
12
24
12
0
6
6
6
0
0
6
6
6
0
0
% A
% Cys:
0
0
0
6
6
0
0
0
0
0
0
0
0
0
6
% C
% Asp:
6
6
6
6
12
12
12
6
12
6
0
6
0
0
0
% D
% Glu:
0
6
6
0
0
0
6
0
18
30
6
30
6
18
30
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
6
12
6
12
0
0
0
0
6
6
6
18
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
6
0
6
12
% H
% Ile:
0
0
0
6
0
0
0
0
12
0
6
6
6
6
6
% I
% Lys:
0
6
6
6
0
6
18
6
6
18
12
12
18
24
0
% K
% Leu:
12
24
0
6
6
0
6
6
0
6
6
0
6
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
6
0
6
0
0
0
% M
% Asn:
0
6
0
6
0
6
0
6
0
6
6
0
0
0
6
% N
% Pro:
6
6
0
18
12
12
6
12
24
6
6
6
6
6
0
% P
% Gln:
0
0
12
0
0
6
0
0
6
0
6
6
6
6
0
% Q
% Arg:
0
0
0
0
0
0
0
0
6
0
0
0
6
6
6
% R
% Ser:
12
6
0
6
30
24
24
24
6
0
12
0
12
12
0
% S
% Thr:
24
0
6
6
6
12
6
6
0
6
18
0
0
0
6
% T
% Val:
18
12
18
6
6
6
6
18
0
0
0
0
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _